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| Genres: | Action, Animation, Comedy, Crime, Drama, Romance, Thriller, . |
| Year: | 2001. |
| Director: | Bobby Farrelly, Peter Farrelly,. |
| IMDB Rating: | 6.10 (5512 votes). |
| Actors: | |
| Molly Shannon | | | Bill Murray | | | William Shatner | Mayor Phlegmming | | Laurence Fishburne | Thrax | | Ben Stein | | | Chris Rock | Osmosis Jones | | David Hyde Pierce | Drix | | Ron Howard | Tom Colonic | | Joel Silver | | | Bobby Farrelly | | | Peter Farrelly | | | Brandy Norwood | Leah | | Kid Rock | Kidney Rock | | Kenny Olson | Kidney Rock | | Jason Krause | Kidney Rock | | Joe C. | Kidney Rock | | Stefanie Eulinberg | Kidney Rock | | Jimmie Bones | Kidney Rock | | Uncle Kracker | Kidney Rock | | Jonathan Adams | Additional Character Voice | | |
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Plot: Frank Detomello catches a cold. The inside of his body is known as the "City of Frank" to its inhabitants, two of which - white blood cell cop Osmosis Jones, and cold tablet Drixorial - team up to fight the invading viruses intent on taking over the City.
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